SubtiBank SubtiBank
Version comparison:

2017-04-09 20:19:272017-03-31 14:40:39

description

ATPase, centromere-like function involved in forespore chromosome partitioning / negative regulation of sporulation initiation

locus

BSU40970

proteinLength

253

geneLength

759

function

forespore chromosome partitioning /
negative regulation of sporulation initiation

product

negative regulator of sporulation initiation

essential

no

ec

names

parA

soj

spo0JA

outlinks

bsupath

parA_4206397_4207158_-1

outlinks

uniprot

P37522

outlinks

subtilist

gene_detail BG10055

outlinks

bsu

BSU40970

genomicContext

[[this]]

categories

[[this]]

Gene

Coordinates

4,206,397 -> 4,207,158

The protein

Catalyzed reaction/ biological activity

regulates [SW|DNA replication] initiation by either inhibiting or activating the [SW|DNA replication] initiator protein [[protein|DnaA]] [Pubmed|21235642]; regulation of ''Spo0A'' expression [Pubmed|10852876]

The protein

Protein family

parA family (according to Swiss-Prot)

The protein

Effectors of protein activity

[[protein|ParB]] inhibits [[protein|ParA]] dimerization and concomitant DNA-binding activity by stimulating [[protein|ParA]] ATPase activity [Pubmed|21235642]

The protein

[SW|Localization]

polar/ septal at the cell membrane [Pubmed|20566861]

polar localization depends on the proton motive force [Pubmed|20566861]

Expression and Regulation

Operons

[[this]]

Expression and Regulation

Other regulations

[[this]]

Labs working on this gene/protein

[SW|Heath Murray], Centre for Bacterial Cell Biology, Newcastle, UK [http://www.ncl.ac.uk/camb/staff/profile/heath.murray homepage]

References

Reviews

20157337, 22934648, 26286503, 26706151, 28075389

References

Original publications

15659156, 11532141, 19450516, 18854156, 10619015, 8866474, 12492861, 9701805, 12950914, 14651647, 19450516, 20566861, 21235642, 10852876, 14563866, 26253537, 22286949, 21911367, 27059541, 27489185