2017-04-09 20:19:272017-03-31 14:40:39
description
ATPase, centromere-like function involved in forespore chromosome partitioning / negative regulation of sporulation initiation
locus
BSU40970
proteinLength
253
geneLength
759
function
forespore chromosome partitioning /
negative regulation of sporulation initiation
product
negative regulator of sporulation initiation
essential
no
ec
names
parA
soj
spo0JA
outlinks
bsupath
parA_4206397_4207158_-1
outlinks
uniprot
P37522
outlinks
subtilist
gene_detail BG10055
outlinks
bsu
BSU40970
genomicContext
[[this]]
categories
[[this]]
Gene
Coordinates
4,206,397 -> 4,207,158
The protein
Catalyzed reaction/ biological activity
regulates [SW|DNA replication] initiation by either inhibiting or activating the [SW|DNA replication] initiator protein [[protein|DnaA]] [Pubmed|21235642]; regulation of ''Spo0A'' expression [Pubmed|10852876]
The protein
Protein family
parA family (according to Swiss-Prot)
The protein
Effectors of protein activity
[[protein|ParB]] inhibits [[protein|ParA]] dimerization and concomitant DNA-binding activity by stimulating [[protein|ParA]] ATPase activity [Pubmed|21235642]
The protein
[SW|Localization]
polar/ septal at the cell membrane [Pubmed|20566861]
polar localization depends on the proton motive force [Pubmed|20566861]
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
Labs working on this gene/protein
[SW|Heath Murray], Centre for Bacterial Cell Biology, Newcastle, UK [http://www.ncl.ac.uk/camb/staff/profile/heath.murray homepage]
References
Reviews
References
Original publications